Meghna Gupta, Ph.D., an assistant professor of chemical physiology and biochemistry at OHSU School of Medicine, is leading research on peroxisomes—subcellular structures essential for breaking down fats and neutralizing harmful substances.
The Focus: Structure and Dysfunction
Gupta discovered previously unseen ultrastructural features within peroxisomes.
Her lab employs cryo-electron microscopy to study peroxisome proteins and their link to metabolic, genetic, and age-related diseases. The central aim of her work is to understand how peroxisome dysfunction contributes to conditions such as adrenoleukodystrophy, Zellweger syndrome, and common metabolic disorders.
A Rapid Rise in Academic Leadership
Gupta’s career trajectory includes ranking ninth in a national fellowship competition in India. She earned her Ph.D. from Jawaharlal Nehru University in 2016 and completed a postdoctoral fellowship at UC San Francisco before establishing her independent lab at OHSU in 2024.